If you run everything aft it has to work.. this means good gear, blocks, the right tackle etc..
I agree that for this kind of the a working autopilot is a huge advantage, being able to move around the boat and tend to things without having to dash back and forth to correct a course or wind angle is really nice.
Headsail halyards (if not furling), spinnaker lines, downhauls, vang if applicable are all good candidates. Depending on the boat I'm not sure I'd run the main halyard aft unless the reefing lines are run aft too. If you have to go to the mast to deal with the reef tack and clew, the halyard may as well be there too. (and see 'autopilot' reference above
Running reef lines aft is the most problematic, as they are going to be the most friction-prone. This can add up to a good bit of good (costly) gear, but it's out there if you want it.