That's what I'm currently doing. I sold a 10 metric ton Columbia 43 last fall and I'm picking up my "new" Fortune 30 - 5 tons - next week.
I won't need to rustle up crew to go out for an evening sail and it won't take an hour at each end to get going and put it to bed.
Years ago every survey of experienced cruisers said 35'-40' was the optimum for long term use.
I have learned through personal experience that they were right.
Big boats are very seductive and exciting to sail but they can quickly become effectively a small business to own & operate.
A business that incurs a major financial loss every year.