Matt - You might want to check out Beth Leonard's book titled The Voyager's Handbook. Additionally, Good Old Boat magazine has been running a three part series called "A bluewater capable yacht", which is an adaptation/excerpt from Beth's book.
I believe the factors you mentioned in your first paragraph are part of the picture for a bluewater boat. But you also have to consider things such as cockpit size and drainage (generally smaller and well-drained for bluewater), deck layout (safe sidedecks, sturdier lifelines, etc.), cabin layout (quality seaberths, handholds, adequate storage/tankage), and additional factors which I'm sure I've missed but others will include.
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