All paint systems I'm aware of (Interlux, AwlGrip, AlexSeal, etc) have specific solvents for prepping the surface. It's an important step - please don't skip it (yes, they are way more expensive than just acetone). If you're just removing bulk dust and residue, then go ahead and use acetone or mineral spirits (neither will damage the gelcoat), but follow up with liberal use of the manufacturer's recommended solvent.
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