I'm not sure if I understand your question. Do you mean a door in a frame or jamb? Is there a possibility of twist or flex in the bulkhead?
My experience with such things would suggest that lots of clearance is good. The tendency is to want a machinist's fit, but even sealed with
epoxy wood swells and moves with the seasons, and there is nothing worse than a door or the like sticking because it swelled. I would say a WORKING clearance of 1/8" is good. Three coats of thickened
epoxy is going to be at least 0.090", most likely more.
Feetup