cruiser, live aboard, bluewater?
Since you have stressed comfort so much, I think it might be helpful (tho'' perhaps not feel like it...) to mention that comfort which is derived from boat systems will turn out to be far less meaningful when cruising than comfort that comes from e.g. crew competence (which keeps one out of trouble and reduces the anxiety level immensely), sound navigation, a solid basic knowledge of weather systems, and a practiced hand at choosing a good anchorage...among many other ''non-system'' skills.
I''m sure you''ll find a lot of folks who will speak endearingly of their breadmaker or efficient reefer or integrated chart/radar/recipe plotter. It''s a tendency we all have given the breadth of clever gadgets available to us today and the generic pitch which bombards us that one can ''buy'' comfort. Just don''t overlook the reality that cruising can be a tough business sometimes, and that comfort is not routinely available on occaision. Your basic skill sets - ultimately - are going to bring you the most satisfaction & fulfillment...and keep the cruising dream going after the cruise has begun, at least IMO.