Seasickness varies a lot from person to person. I know people who have never been seasick.
But I have known others for whom there is no cure. When I was in the navy I watched a few people who never got over it, and I'm tellin' ya it was awful for them. The rest of us would get seasick, throw up and go on, but these few were just incapacitated.
I have seen no way to predict what will work for who, but I'm betting that most medications work.
Me? I get seasick, but nothing that knocks me out. I throw up for the first few days, then I'm better and it doesn't come back unless I am away from the sea for some months. Then I gotta start all over.
When you come to a "Y" in the road, take it....Yogi Berra