It'll probably be nippy, so it would be nice to have some way to heat the cabin. Especially in the morning. It's tough to wake up in a cold, dark boat in November.
The winds will likely blow stronger and more consistently from the north. This will build up some short steep waves in the southern bay where they will have had the whole expanse of the bay to build up.
Crossing the Potomac that time of year can be fun too. I'd choose my weather windows carefully. A small craft warning in the bay during the summer often means a great time to go sailing, but in November in the lower bay it probably should be respected.
I'm planning one one more week long cruise out of Deltaville in October, and hope to do some more short sails in November and December, weather permitting.
Gemini Catamaran Split Decision