[Melrna]

I don't know of any charters here that will do a one way charter. You might check with Florida Yacht Sales and Charter in Miami.
I am doing that route this week. Can be an easy route. Depends on your draft for the inside route. Outside route is nice but limited anchorages.
Dinghy is a must for most places to get to shore if you are not spending any time in a marina for which are expensive.