Availability and quality of facilities differ everywhere you go. When I am anchored out I miss hot showers
I have hot water on board but of course without proper facilities on land you are limited to military showers and always conserving water and fuel.
Depending on individual marinas you can have this challenge resolved since there are usually showers on shore, but again, the quality of these vary. One thing I find is that not all marinas have laundry facilities so that becomes another challenge for the live aboard. I am anchored at the moment and I currently kayak about 2 miles and walk about 1 mile (in total) to do my laundry.
Fuel is another challenge in certain situations, but again this can be resolved with alternative power sources like wind and solar. I personally just live with the inconvenience of having to get fuel for the genset about once a week.
I don't miss the old cost of living and being tied to all the things that eventually own you and control your life