Near the end of August I will be moving my new (to me) Hardin 45 from the Lake Pontchartrain via the ICW to the River then down to Venice and out Tiger pass going outside to Intercoastal City LA.
There's been lots of flood gate work at Seabrook, with big cofferdam blocking access from the Lake into the Industrial Canal. You likely already know this, I'm just sayin' just in case. You may have to take the long way around via the Rigolets and ICW or Ostrica/Baptiste Collette if you're trying to get into the river above Venice.
No doubt I'm stating the obvious. Enjoy your trip!