Well, yes and no. Although we may be splitting hairs a bit here, please read the following statement from Blue Sea Systems regarding selection of their ANL fuses (bolding mine):
"Because ANL fuses behave differently than all other circuit protection devices, that is, their blow point value ranges from 140 to 266% of nominal value, the 80% rule doesn't work. It is necessary to use a different procedure to select a suitable ANL fuse. To choose a suitable ANL fuse, refer to the ANL Fuse Blow Point table above. According to the table, a 100A ANL fuse has a blow point of 175A. Therefore, a 100A ANL provides suitable protection for the 4 gauge AWG circuit in this example."
This is particularly relevant to the smaller ANL sizes, where the blowpoint -- after 8 minutes -- can be as much as 266% of the nominal rating.