I would think it depends on the size of your boat. I always single hand but on my boat it's really no different than with crew, then I just don't need to handle the jib.
I've got everything run back to the cockpit, except for the halyards, but I operate them by standing on the cabin berths.
As far as safety it's the same - except for MOB of course - that would be bad. I sail in 0 to 2 foot seas at worst and the water is temperate so unless I'm out of the cockpit there is no real danger of going overboard.
kpgraci (Ken Graci)
New Orleans, LA
'73 ODay 22
If one does not know to which port one is sailing, no wind is favorable. - Lucius Annaeus Seneca (c. 4 BC - 65 AD)