The DOS has placed a number of spots on the "really, there are safer places to visit" list. If you really want or need to go there, you still go. If you'd rather not worry about those kind of problems, you skip those places until things change.
It really is that simple. Places don't get on that list because of one or two isolated incidents, they get on the list because of repeated problems. Pickpockets, you can take reasonable precautions against. Kidnappers and cartel wars against local police, not so easy to plan for. If you have to ask how dangerous it really is...it might be easier to go someplace else this year.