La Paz has a good cruiser's net with the weather, ch 22 at 8 am. Weather in LP is generally affected by the land masses and is not the same as the sea.
The most common route to PV from LP is to go inside the islands Todos Santos and Cerralvo to Bahia de los Muertos the first day. It should be a downhill run. Watch out. The wind between the mainland (baja) and the islands can get wicked, and may be as much as 4 times (or more) than forecast or observed in the sea. Stop at the Giggling Marlin (the palapa at the far right of the bay) for drinks. On SSB, Don forecasts weather at 7:15 pm std. mountain time 6.5160 mghz.
From there continue south to Los Frailes. From there you should have a pleasant broad reach to PV, about 60 hours or so.
With that route you can shake down the boat and the crew before you make the long leg across.
Expect winds to be predominately from the N to NW, although it seems to vary throughout the day. Seas will be in proportion to the weather.
Check out
Baja California's Traveling and Living Online Magazine for daily weather and forecasts. Have a good ride.
PS, I forgot to add, if you're not familiar with LP, check the tide times. You want to go with the outgoing tide, and for gods sake
STAY WITHIN THE MARKERS. The markers don't make sense, but it's the only way out for a keelboat.