Lionfish are excellent table fare, however, handling them can be extremely dangerous. The tip of each spine is a small hypodermic needle filled with toxin. While an adult is unlikely to die from an inflicted wound, the pain can be absolutely excruciating.
Hook and line fishing is the best advice I have. Use strips of cleaned, washed squid, whole shrimp, live or dead, chunks of cut fish, etc..., rigged on a 1/0 wide-gap hook and a top & bottom rig. Fish the open patches of sand between the reefs and you'll find lots of fish.
Outside tropical areas, fish the shallow drop-offs, depths ranging 12 to 10 feet are usually the most productive, locations where baitfish and shrimp are prevalent and dissolved oxygen levels are highest. Schooling species, striped bass, bluefish, croaker, spot, etc..., tend to migrate through these areas during tidal changes. Shallow water areas tend to be best during incoming tide, while the outer edges of shallow drop-offs are often highly productive during the ebb.
Trolling with artificial lures from a moving sailboat is rarely productive for a variety of reasons. More often than not, the boat is traveling much too fast unless you're trying to catch pelagic species, tunas, billfish, some species of sharks. And, anything over 6 knots is often too fast for them as well. Additionally, those species tend to roam the canyon edges and offshore lumps, locations where most boaters do not frequent. Sure, you can luck across a mahi or tuna once in a while, but the odds are not favorable.