Seems like the question is more about her abilities than the boat's. And, as you know, that's not something that anybody but her can work with.
One question that would change things 'boatwise' is what kind of sailing is she looking to do? Daysail? Weekender? 7 day passages? Ocean crossings?
Also, what boat experience does she already have?
And, while I understand the desire to do everything 'normal', facts is facts. Both my father and my grandfather are in wheelchairs, and while my grandfather is a recent inductee to that club, my father has been sporting the wheels for most of two decades.
At the end of the day, he finds it useful to simply recognize that he's not of the walking variety of people, and a few changes to his environment are appropriate.
Obviously he's not her, and all of that. But if she allows herself a few conveniences, she'll find things like galley work (especially getting through the icebox), sail trimming, and navigating the companionway ladder
much more challenging than it needs to be.
But, that's another issue, right? Back to the question.. what kind of sailing?