...My wife suffers from terrible sea sickness; according to her, pretty mild from my view.....
Not going to be snarky, but just suggesting you treat this like it is terrible, not mild. Seems you are, as you’re looking for solutions. Does she want solutions, or would she prefer not to do this? No drug will fully make this a non-issue. Most won’t work, after symptoms begin and it can’t be healthy to take them every day.
The scopolamine patch is generally considered the most effective, but does have side effects. If your wife tolerates it well, as the last post implies, why not stick with it? In high doses, it is used by criminals because the victim does not present any inebriation, but is also unaware of what they are doing and fully compliant. Executives in Columbia were seen on security video withdrawing money from ATMs or giving bank instructions the criminal instructed them to. They woke up (if they didn’ overdose) with no recollection.
In small doses, short term memory loss is a common side effect. I cruised with a friend that asked me the same question 4 times in a row. It was bizarre. He had no recollection of the question just seconds earlier. Never, ever apply a second patch, if the first isn’t working. Unless hallucinating, however, you may not be able to tell that your wife is having side effects and she many not remember. Very weird drug.
Another drug is sturgeron (spelling?). Not available in the US, but I understand it is in Canada. However, it is believed it could contribute to developing Parkinson’s in one’s elder years. Even if that one in a thousand, those odds are too high for me.
Living on seasickness drugs is not a great solution. Hopefully, her anxiety will subside and this will cure itself. It will only happen if she wants it to.