Moser Channel, just west of Marathon, has a fixed bridge with 65' clear that you should be able to make at low tide depending upon what's sticking up above your mashead (see Chart 11451). You'll have to tip-toe through Florida Bay from Cape Sable a bit but with only 5' of draft, thats not a problem. From the Shark River to the Bridge is about 40 miles which you should be able to do during daylight.